What is CBD?

Hemp plants contain over 140 naturally occurring, active compounds called cannabinoids. Cannabidiol (CBD) is one of the many cannabinoids found in the marijuana and industrial hemp plant.  Unlike its close relative, THC (Tetrahydrocannabinol), CBD is completely non-psychoactive. This allows us to benefit from the many health properties of the Cannabis plant without the negative side effects of “getting high.” Because of this, CBD became a very popular option for those seeking a natural alternative for certain conditions. 

Endocannabinoid System

The endocannabinoid system (ECS) is a network of messengers and receptors that regulate the way your body communicates with the brain. The messengers called cannabinoids to bind to the receptors located throughout your body. Cannabinoids are found in three different forms which include endocannabinoids ( produced in the body), phytocannabinoids ( produced by the hemp plant) and pharmaceutical cannabinoids ( produced by man). There are also two key endocannabinoids in your body called 2-AG and anandamide. Anandamide is nicknamed the “bliss molecule,” because studies believe it aides in modulating mood, memory, appetite, fertility, and is even believed to halt the proliferation of cancer cells.  2-AG is believed to regulate sleep, immunity, pain, and appetite. Although your body makes your own endocannabinoids as needed, they can be broken down very quickly by enzymes.

That's where CBD comes into play.... it helps prevent the breakdowns of these helpful molecules. Much like a daily vitamin, CBD, one of the many cannabinoids found in the hemp plant, supplements the Endocannabinoid System, which plays a vital role in optimal daily life. When the ECS is in balance, one experiences homeostasis. 

History behind CBD

Dating back to the ancient civilizations, it was some of the first people on earth who discovered and identified the differences between hemp and began using cannabidiol for various purposes. Archaeologists believe the plant species “Cannabis Sativa,” dates back 10,000 years ago and was likely one of the first crops planted by early man. These people also identified that hemp seeds have high levels of protein, vitamins, and essential fatty amino acids. During this period, hemp seeds were used so frequently that they became essential to human civilization. Hemp has long been grown for a variety of purposes: its seeds can be used to produce food and cosmetics, and its stalks are found in products ranging from construction materials to clothing to biofuels.

As one of the many useful compounds in the hemp plant, CBD has been used to treat ailments for millennia. However, the individual compounds in cannabis remained unidentified until Dr. Raphael Mechoulam revealed the structure of THC and CBD in the early 1960s. In the 1980s, President Ronald Reagan poured tens of millions of dollars into a study to prove that cannabis damages the human brain. But rather than showing how cannabis harms the brain, the Reagan administration ended up subsidizing a series of studies that culminated in the discovery of the endocannabinoid system, expanding our understanding of how cannabinoids interact with the human body. Due to the role of endocannabinoids in this system, the system was officially named the Endocannabinoid System (ECS).

HEMP VERSUS MARIJUANA Understanding the Difference

Hemp and Marijuana are terms that are often used interchangeably to describe any cannabis plant or its derivative. These two plants differ in their cannabinoid and THC ratios but come from the same plant species Cannabis Sativa. Although they are both cannabis plants, hemp and marijuana differ notably in their genetic makeup and are cultivated and harvested in different ways. Hemp plants are typically tall and thin and cultivated to produce foods, oils, paper, textiles, and high CBD extractions. CBD is found in varying levels in both plant varieties. The plant commonly referred to as marijuana contains higher amounts of THC (tetrahydrocannabinol), the psychoactive component.

While they have different chemical properties, according to the Federal Government, the industrial hemp is defined as Hemp, the plant Cannabis sativa L. and any part of such plant, whether growing or not, with a [THC] concentration of not more than 0.3 percent on a dry weight basis. The magic number is "0.3%" which is defined by the 2018 Farm Act Bill. All of the Pure Therapy products are derived from crops grown in accordance with the Farm Act Bill.

FULL SPECTRUM VERSUS CBD ISOLATE CHOOSING WHICH PRODUCT IS RIGHT FOR YOU

FULL SPECTRUM

Full-spectrum products contain naturally occurring cannabinoids (with trace amounts of THC), plant terpenes, flavonoids, vitamins and minerals of the original hemp source.  The plants are processed as little as possible to preserve the natural profile of the plant. It is like the difference between fresh pressed orange juice at your local farmer's market versus bottled orange juice the grocery store. Research shows that the whole plant extract makes a difference in the effectiveness of the products. These compounds work together, multiplying the potential health benefits of each of the product components in what is known as the " Entourage Effect".

CBD ISOLATE

CBD isolate is cannabidiol in its purest form- a full spectrum product that has been further processed to remove terpenes, flavonoids, and other plant compounds. All that remains is the white powder that is at least 99% pure CBD with trace cannabinoids and 0% THC. This powder can be used to make various CBD products such as tinctures, creams, edibles and more. People who are subject to drug testing or have sensitivities to full-spectrum products may prefer an isolated form.

CBD AND DRUG TESTING

It is unlikely that a urine drug screen (UDS) would show up positive for THC with a patient taking a pure CBD isolate. On the other hand, Full Spectrum Pure Therapy products may contain trace amounts of THC ( less than 0.3%) are therefore more likely to test positive on a UDS. The only way to be completely safe is to stop all usage of any isolate or full-spectrum product prior to scheduled testing or just be honest with your medical provider or employer. CBD products have become so popular that most people are aware of them.

MAJOR TYPES OF CBD PRODUCTS WHICH PRODUCT TO CHOOSE

If you have read about cannabinoid oil in-depth, you are aware of the numerous ways it can be consumed. Each individual’s body is different and hence, responds differently to these products. Each individual should try the different capsules, oils, and creams and find out which products work best for them. Most people report that the drops are the best and easiest way to consume oil but do not always have the best favor. Some people prefer the vape form because it has a faster onset but must be very careful regarding the carrier oil. There is a risk of fatty acid pneumonia when using certain vegetable oils as the carrier oil. A dosage that will be effective ranges varies from person to person, and there is not a standardized guide for dosing. A large dose of cannabinoids could cause GI cramping and be less effective. In the case of the CBD oil, “Less is more” is more than often the case. With continuous practice and some patience, you will realize the quantity that works optimally for you.

TINCTURES

CBD oils are a popular choice among CBD enthusiasts because they are very easy to use. When consumed sublingually (under the tongue), the efficacy of CBD reaching your bloodstream is maximized. Tinctures are great for those who have trouble swallowing capsules or soft gels. Available in both Full-Spectrum and THC-Free forms. 

CAPSULES/SOFT GELS

If you value convenience, CBD capsules or soft gels maybe your best option. When you select a CBD capsule, you never have to worry about measuring your preferred dosage or mixing your CBD oil with food or beverages. Great for the one-the go CBD user!
 

TOPICALS

CBD is known for its potential anti-inflammatory applications, making a topical product an optimal choice! In addition, CBD appears to contain powerful antioxidants that could reduce the free radical damage that accelerates collagen loss. Collagen loss leads to sagging skin and wrinkles. By applying CBD topically, the activity of the CBD directly targets the area of application.

HEMP VERSUS MARIJUANA Understanding the Difference

Hemp and Marijuana are terms that are often used interchangeably to describe any cannabis plant or its derivative. These two plants differ in their cannabinoid and THC ratios, but come from the same plant species Cannabis Sativa. Although they are both cannabis plants, hemp and marijuana differ notably in their genetic makeup and are cultivated and harvested in different ways. Hemp plants are typically tall and thin and cultivated to produce foods, oils, paper, textiles and high CBD extractions. CBD is found in varying levels in both plant varieties. The plant commonly referred to as marijuana contains higher amounts of THC (tetrahydrocannabinol), the psychoactive component.

While they have different chemical properties, according to the Federal Government, the industrial hemp is defined as Hemp, the plant Cannabis sativa L. and any part of such plant, whether growing or not, with a [THC] concentration of not more than 0.3 percent on a dry weight basis. The magic number is "0.3%" which is defined by 2018 Farm Act Bill. All of the Pure Therapy products are derived from crops grown in accordance with the Farm Act Bill.

FULL SPECTRUM VERSUS CBD ISOLATE choosing which product is right for you

FULL SPECTRUM

Full-spectrum products contain naturally occurring cannabinoids (with trace amounts of THC), plant terpenes, flavonoids, vitamins and minerals of the original hemp source.  The plants are processed as little as possible to preserve the natural profile of the plant. It is like the difference between fresh pressed orange juice at your local farmer's market versus bottled orange juice the grocery store. Research shows that the whole plant extract makes a difference in the effectiveness of the products. These compounds work together, multiplying the potential health benefits of each of the product components in what is known as the " Entourage Effect".

CBD ISOLATE

CBD isolate is cannabidiol in its purest form- a full spectrum product that has been further processed to remove terpenes, flavonoids, and other plant compounds. All that remains is the white powder that is at least 99% pure CBD with trace cannabinoids and 0% THC. This powder can be used to make various CBD products such as tinctures, creams, edibles and more. People who are subject to drug testing or have sensitivities to full-spectrum products may prefer an isolated form.

CBD AND DRUG TESTING

It is unlikely that a urine drug screen (UDS) would show up positive for THC with a patient taking a pure CBD isolate. On the other hand, Full Spectrum Pure Therapy products may contain trace amounts of THC ( less than 0.3%) are therefore more likely to test positive on a UDS. The only way to be completely safe is to stop all usage of any isolate or full-spectrum product prior to scheduled testing or just be honest with your medical provider or employer. CBD products have become so popular that most people are aware of them.

MAJOR TYPES OF CBD PRODUCTS WHICH PRODUCTS TO CHOOSE

If you have read about cannabinoid oil in-depth, you are aware of the numerous ways it can be consumed. Each individual’s body is different and hence, responds differently to these products. Each individual should try the different capsules, oils, and creams and find out which products work best for them. Most people report that the drops are the best and easiest way to consume oil but does not always have the best favor. Some people prefer the vape form because it has a faster onset but must be very careful regarding the carrier oil. There is a risk of fatty acid pneumonia when using certain vegetable oils as the carrier oil. A dosage that will be effective ranges varies from person to person and there is not a standardized guide for dosing. Most people report relief from sleep and anxiety lower doses such as 10-20 mg daily in divided doses and higher doses up 50 mg daily for those people seeking freedom from pain. If you are a beginner, you should start with a small dose and work your way up. Most people prefer to take divided doses throughout the day. Indulge in a higher number of smaller courses over a day as compared to a bigger dose. Use the same ratio and dose for a few days, and observe its effect on you. However, keep it in mind that you should not take an overdose. A large dose of cannabinoids could cause GI cramping and be less effective. In the case of the CBD oil, “Less is more” is more than often the case. With continuous practice and some patience, you will realize the quantity that works optimally for you.

TINCTURES

CBD oils are a popular choice among CBD enthusiasts because they are very easy to use. When consumed sublingually (under the tongue), the efficacy of CBD reaching your bloodstream is maximized. Tinctures are great for those who have trouble swallowing capsules or soft gels. Available in both Full-Spectrum and THC-Free forms. 

CAPSULES/SOFT GELS

If you value convenience, CBD capsules or soft gels maybe your best option. When you select a CBD capsule, you never have to worry about measuring your preferred dosage or mixing your CBD oil with food or beverages. Great for the one-the go CBD user!
 

TOPICALS

CBD is known for its potential anti-inflammatory applications, making a topical product an optimal choice! In addition, CBD appears to contain powerful antioxidants that could reduce the free radical damage that accelerates collagen loss, Collagen loss leads to sagging skin and wrinkles. By applying CBD topically, the activity of the CBD directly targets the area of application.

The Entourage Effect: Compounds Working Together

Some researchers believe that cannabis is more therapeutically beneficial when all the compounds found in the plant — including its a wide range of cannabinoids, terpenes, and flavonoids — are administered together. The theory known as the entourage effect suggests that all of the various chemical compounds in cannabis interact and work together synergistically to produce therapeutic benefits and regulatory effects.

The Entourage Effect: Compounds Working Together

Some researchers believe that cannabis is more therapeutically beneficial when all the compounds found in the plant — including its a wide range of cannabinoids, terpenes, and flavonoids — are administered together. The theory known as the entourage effect suggests that all of the various chemical compounds in cannabis interact and work together synergistically to produce therapeutic benefits and regulatory effects.

Safety Profile of Cannabidiol (CBD)

Side effects of CBD include nausea, fatigue, and irritability. CBD can increase the level in your blood of certain medications such as coumadin, and it can raise levels of certain other medications in your blood by the exact same mechanism that grapefruit juice does. A significant safety concern with CBD is that it is primarily marketed and sold as a supplement, not a medication. Currently, the FDA does not regulate the safety and purity of dietary supplements. So you cannot know for sure that the product you buy has active ingredients at the dose listed on the label. In addition, the product may contain other (unknown) elements. We also don’t know the most effective therapeutic dose of CBD for any particular condition. This is the reason why it is so important that you receive CBD products from a trusted source that provides you with third-party testing. When determining your product source, please do not hesitate to request Certificates of Analysis which should examine potency and quality of the oil. To learn more about phytocannabinoids (CBD) visit our Educational Blog page.

Safety Profile of Cannabidiol (CBD)

Side effects of CBD include nausea, fatigue, and irritability. CBD can increase the level in your blood of certain medications such as coumadin, and it can raise levels of certain other medications in your blood by the exact same mechanism that grapefruit juice does. A significant safety concern with CBD is that it is primarily marketed and sold as a supplement, not a medication. Currently, the FDA does not regulate the safety and purity of dietary supplements. So you cannot know for sure that the product you buy has active ingredients at the dose listed on the label. In addition, the product may contain other (unknown) elements. We also don’t know the most effective therapeutic dose of CBD for any particular condition. This is the reason why it is so important that you receive CBD products from a trusted source that provides you with third-party testing. When determining your product source, please do not hesitate to request Certificates of Analysis which should examine potency and quality of the oil. To learn more about phytocannabinoids (CBD) visit our Educational Blog page.

Thanks to advancements in technology and clinical trials, researchers were able to reverse engineer what they’d discovered, trace back through the metabolic pathways of various cannabinoids, and uncover an entirely unknown signaling system between the CB1 and CB2 receptors in our bodies and receptors found in Cannabis compounds, which they called “endocannabinoids.” Clinical trials are underway to determine if CBD is therapeutic for many different conditions such as seizures, inflammation, stiff muscles, joint pain, chemotherapy side effects, migraines, post-traumatic stress disorders, chronic pain, and anxiety. CBD is rapidly gaining in popularity for both humans and pets. To learn more about CBD research, please visit our Education page.